Monday, December 21, 2009

I'm Pushing The NMDAR In Shiners Paper

I've spent much of my time for the last 5 days working on our manuscript, "Sexual Dimorphism in the Teleost Central Nervous System Varies With Spawning Strategy" by Stallsmith et al. It's just about ready to submit to the journal NeuroReport, with our comparisons of brain features between males and females in scarlet (L. fasciolaris), silverstripe (N. stilbius) and telescope (N. telescopus) shiners. I'll let the Abstract explain it broadly:

ABSTRACT
Lythrurus fasciolaris is a sexually dimorphic fish with peak dimorphism during breeding season, as indicated by size and nuptial coloration, while Notropis stilbius and N. telescopus are not. This study asked if phenotypic sexual dimorphism is reflected in the brain as indicated by relative size of the brain, and also differences in expression of NMDA receptors involved in learning and memory. Reproductive condition male L. fasciolaris have significantly larger brain to standard length ratios than do females, but male N. stilbius and N. telescopus do not. During breeding season L. fasciolaris males have significantly higher expression of NMDA receptors than do females while in the non-sexually dimorphic species, Notropis stilbius and N. telescopus, males and female expression levels are not significantly different indicating that NMDA receptors undergo pronounced sex-specific regulation only in the strongly sexually dimorphic species.

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